LeCanadian

Top Menu

  • Login
  • Archives
  • Les Actualités
  • Advertising
  • Sexy Pages
  • Contact Us

Main Menu

  • Home
  • Business
  • Entertainment
  • Foodie
  • Headline
  • Health
  • Editorials
  • Lifestyle
  • Sports
  • UFO · Exopolitics
  • City
  • Sexuality
  • Dating
Sign in / Join

Login

Welcome! Login in to your account
Lost your password?

Lost Password

Back to login
  • Login
  • Archives
  • Les Actualités
  • Advertising
  • Sexy Pages
  • Contact Us

logo

Header Banner

LeCanadian

  • Home
  • Business
  • Entertainment
  • Foodie
  • Headline
  • Health
  • Editorials
  • Lifestyle
  • Sports
  • UFO · Exopolitics
  • City
  • Sexuality
  • Dating
  • 7 reasons why online casinos are so popular in Ontario

  • La Commission indépendante soutient le recours de la Cour suprême contre le déni des droits des non-francophones par le Québec

  • Independent Commission endorses Supreme Court of Canada challenge against Quebec’s denial of rights to non-francophones

  • Ottawa International Crafts & Book Expo 2023: An assembly of literary brilliance

  • Diane Descôteaux – Une haïkiste passionnée: Le Salon d’Ottawa

Health
Home›Health›STUDY: Ultra-Low Doses of Monsanto’s Roundup Cause Massive Gene Alterations in Lab Rats, Leading to Other Health Problems

STUDY: Ultra-Low Doses of Monsanto’s Roundup Cause Massive Gene Alterations in Lab Rats, Leading to Other Health Problems

By admin
June 1, 2016
1761
0
Share:

New research shows that ultra-low dose exposure to glyphosate, the active ingredient in Monsanto’s Roundup, causes massive gene alterations in lab rats, according to a study published in the journal Environmental Health.

The report is the first in a series of studies observing the effects ultra-low doses of glyphosate have on gene expression profiles and the subsequent epigenetic changes, or changes that become inherited patterns of gene function, which can lead to other health problems down the road.

The research is being led by Molecular Geneticist Dr. Michael Antoniou with King’s College in London, and Cellular and Molecular Biologist Dr. Robin Mesnage, who successfully reverse-engineered the co-formulants in Roundup.

This was a major achievement considering that the identity of the herbicide’s “inert ingredients,” as well as their health effects on humans, were unknown and poorly understood prior to Mesnage’s discovery, which found that these supposed “inactive” ingredients may be more dangerous to humans than glyphosate alone.

Research group studies impact of low-dose chemical exposure on gene expression

Currently, Dr. Antoniou is using a bioinformatics software program called Qlucore Omics Explorer to analyze the effects ultra-low doses of glyphosate have on “gene expression profiles (transcriptomes), protein profiles (proteomes), and small molecule metabolite profiles (metabolomes) in rats and cell cultures.”

His research group, Gene Expression & Therapy Group, uses “cell and molecular analytical approaches to investigate transcriptional and post-transcriptional events that regulate gene expression including in response to various environmental stimuli,” such as commonly used pesticides and other chemical pollutants.

GETG is particularly interested in how brief chemical exposure during fetal development and early on in life permanently impacts gene control, as well as the effects of low-dose chemical exposure on the endocrine system.

“Such a fixed change in gene expression pattern can lead to all kinds of problems later in life ranging from obesity, diabetes, a propensity to certain cancers and so on,” said Dr. Antoniou.

Could herbicides be the cause of animal deformities in Argentina?

If glyphosate, even in ultra-low doses, can alter gene expression during fetal development, is it possible that the herbicide can also cause severe deformation in animals?

On Monday, the Daily Mail published a shocking report revealing horrific animal mutations occurring in Argentina, the world’s largest user of glyphosate.

The mutations have quadrupled since Argentina upped its production of genetically modified soy, a crop designed to withstand high doses of Roundup. Farmers and the local media are blaming herbicides.

Rats exposed to ultra-low doses of Roundup suffer gene alterations

Earlier studies showed that ultra-low, environmental doses of Roundup caused damage in lab rats, which was observed in their urine, blood chemistry and anatomy.

Dr. Mesnage analyzed the transcriptomes of the livers and kidneys of ten rats exposed to ultra-low doses of Roundup for two years, as well as ten unexposed controls. The team used principle component analysis (PCA) visualization, heat map visualization and statistical analysis to observe the effects.

“Rats have around 28,000 genes, only a subset of which will be switched on in the liver and in the kidney. Each gene is a dimension of analysis so you have 28k variables, which you need to reduce to something manageable,” explains Dr. Antoniou.

“Using a PCA visualization, Qlucore allows you to graphically represent all these variables in just three dimensions, so that each animal occupies a particular location. Very quickly you can see how each animal relates to another and any treatment-related effect. If a number of animals are clustered together, you know that the effect is the same.”

Heat map visualization highlights genetic activity in rats’ organs

“Heat map visualizations show the activity of each gene for each rat organ so you can see the variation in the group and whether it is homogenous,” Dr. Mesnage adds.

Using these techniques, researchers observed that the rats treated with Roundup had massive alterations in gene expression, while the control group did not.

Dr. Antoniou and Dr. Mesnage will continue their research using technology that allows them to “make predictions based on molecular ‘signatures.'”

“If you see an alteration in a certain pattern of gene function, you can compare that pattern to another batch of genes to see if the signature matches. By taking those alterations and looking at them collectively, you could predict over time that a certain health problem will be the outcome,” says Dr. Mesnage.

If such signatures can be identified, researchers will be able to conduct animal studies much faster, in a matter of months compared to years.

“Even though the exposure would be short, we are interested in whether we might still see an alteration in gene expression patterns in the blood, liver and kidney, even if the animal doesn’t show any overt health problems,” Dr. Mesnage adds.

Sources:

News-Medical.net
DailyMail.co.uk
KCL.ac.uk
EHJournal.BioMedCentral.com
NaturalNews.com
NaturalNews.com
Science.NaturalNews.com

Read More..

Post Views: 1,906
Previous Article

EXCLUSIVE: Health Ranger Launches New Independent Science ...

Next Article

While Insisting Marijuana Has no Medicinal Value ...

0
Shares
  • 0
  • +
  • 0
  • 0
  • 0
  • 0

Related articles More from author

  • Health

    China’s Massive Amount of Immunotoxic 5G Networking and the Wuhan Coronavirus: The Emperor’s New Virus

    April 7, 2020
    By admin
  • Health

    Pharmacological studies prove the therapeutic effects of many active components from Chinese herbal medicine on Alzheimer’s disease and dementia

    June 21, 2019
    By admin
  • Health

    Selenium – What Is it and Where Do I Get It?

    April 29, 2016
    By admin
  • Health

    Why Black Tea Contains Cancer Causing Chemicals, But Green Tea Prevents Cancer

    March 16, 2016
    By admin
  • Health

    Dieting: Dr. Oz Pure Garcinia Cambogia Extract – Where to Buy Guide.

    October 20, 2015
    By admin
  • Health

    Stepping outside the medical fortress

    May 1, 2020
    By admin

Featured Petition

  • Bell Baker’s John Summers – Stop a Crime Against Humanity – What would his Mother think?
  • John E Summers: Ottawa Lawyer Attacks Motherhood and Civil Rights – Support His Disbarment
  • Stop Ottawa Lawyer John Summers’, Marcella Carby-Samuels’ & David Tenenbaum’s Ab
  • Week
  • Month

Week

Sorry. No data so far.

Month

  • 7 reasons why online casi... In the ever-evolving landscape of entertainment and lei...

Popular on The Le Canadian

  1. The Independent Canadian Commission on Civil and Human Rights
  2. AgoraCosmopolitan
  3. Ottawa Market
  4. Agora Publishing Consortium
  5. Le Journal Canadien
  6. Dominion: Food News
  7. LeCanadian.com
  8. The Ottawa Star
  9. Capitalistocracy.com
  10. Agora Books Author House
  11. First Nations Press
  12. The Etiquette Show
  13. Ontario People's Front





Mark's



Recent Posts

  • 7 reasons why online casinos are so popular in Ontario
  • La Commission indépendante soutient le recours de la Cour suprême contre le déni des droits des non-francophones par le Québec
  • Independent Commission endorses Supreme Court of Canada challenge against Quebec’s denial of rights to non-francophones
  • Ottawa International Crafts & Book Expo 2023: An assembly of literary brilliance
  • Diane Descôteaux – Une haïkiste passionnée: Le Salon d’Ottawa
  • Diane Descôteaux – Une haïkiste passionnée: Le Salon d’Ottawa
  • How Canadians can access online casinos through mobile phones
  • Comment gérer un retard de vol ?
  • 5 ways sudoku boosts brain health
  • 10 tips to successfully market your law firm

Most Viewed Posts

  • Automated China –Mass-Producing the Future (61,386)
  • Health: Shampoo Helps Hair Loss Sufferers (57,955)
  • Citizens of Italy unleash mass protests against mandatory vaccination law (39,213)
  • Why Investors are Putting Their Money on High-End Real Estate (37,248)
  • Montréal : le cœur battant de la génération Y (37,092)
  • Une Autre Facette de Richard Lipman : Le Soutien d’un Psychologue à la Fondation Fauna (32,515)
  • Introduction To How And Where You Can Trade CFDs (30,171)
  • Canada’s Property Values Rise, In Spite of Signs of Market Slowdown (21,170)
  • “Not Gonna Write Poems” A Poetry Book by Dr. Michael Lee: Could He Be The Next Shel Silverstein? (17,367)
  • Smoking is Still a Problem in Society – But it’s a Problem That’s Being Addressed (16,166)

Visitors

  • Home
  • Business
  • Entertainment
  • Foodie
  • Headline
  • Health
  • Editorials
  • Lifestyle
  • Sports
  • UFO · Exopolitics
  • City
  • Sexuality
  • Dating